| Item type |
学術雑誌論文 / Journal Article_04(1) |
| 公開日 |
2019-01-07 |
| タイトル |
|
|
タイトル |
Clinical Perspectives of Genetic Analyses on Dyslipidemia and Coronary Artery Disease |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.24517/00053013 |
|
ID登録タイプ |
JaLC |
| 著者 |
Tada, Hayato
Kawashiri, Masa-aki
Yamagishi, Masakazu
|
| 著者別表示 |
多田, 隼人
川尻, 剛照
山岸, 正和
|
| 提供者所属 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
金沢大学附属病院循環器内科 |
| 書誌情報 |
Journal of Atherosclerosis and Thrombosis
巻 24,
号 5,
p. 452-461,
発行日 2017
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1340-3478 |
| NCID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11018976 |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.5551/jat.RV17002 |
| 出版者 |
|
|
出版者 |
日本動脈硬化学会 = Japan Atherosclerosis Society |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We have learned that low-density lipoprotein (LDL) cholesterol is the cause of atherosclerosis from various aspects, including a single case with familial hypercholesterolemia, other cases with different types of Mendelian dyslipidemias, large-scale randomized controlled trials using LDL cholesterol lowering therapies, and Mendelian randomization studies using common as well as rare variants associated with LDL cholesterol levels. There is no doubt that determinations of genotypes in lipid-associated genes have contributed not only to the genetic diagnosis for Mendelian dyslipidemias but also to the discoveries of novel therapeutic targets. Furthermore, recent studies have shown that such genetic information could provide useful clues for the risk prediction as well as risk stratification in general and in particular population. We provide the current understanding of genetic analyses relating to plasma lipids and coronary artery disease. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This article distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License. |
| 権利 |
|
|
権利情報 |
Copyright © 日本動脈硬化学会 Japan Atherosclerosis Society |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連URI |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.jstage.jst.go.jp/browse/jat/-char/ja |
|
|
関連名称 |
https://www.jstage.jst.go.jp/browse/jat/-char/ja |
| 関連URI |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
http://www.j-athero.org/ |
|
|
関連名称 |
http://www.j-athero.org/ |
ME-PR-TADA-H-452.pdf (465.7 kB)
.png)
