| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2019-04-22 |
| タイトル |
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タイトル |
Detection of sentinel lymph node using contrast-enhanced agent, Sonazoid ™ , and evaluation of its metastasis with superb microvascular imaging in oral and oropharyngeal cancers: a preliminary clinical study |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
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|
ID登録 |
10.24517/00053838 |
|
ID登録タイプ |
JaLC |
| 著者 |
Wakisaka, Naohiro
Endo, Kazuhira
Kitazawa, Tomohiro
Shimode, Yuzo
Kato, Koroku
Moriyama-Kita, Makiko
Koda, Wataru
Ikeda, Hiroko
Ishikawa, Kazuya
Ueno, Takayoshi
Nakanishi, Yosuke
Kondo, Satoru
Sugimoto, Hisashi
Yoshimura, Kenichi
Tsujii, Hiroyuki
Kawashiri, Shuichi
Omoto, Kiyoshi
Yoshizaki, Tomokazu
|
| 著者別表示 |
脇坂, 尚宏
遠藤, 一平
加藤, 広禄
喜多, 万紀子
香田, 渉
池田, 博子
石川, 和也
上野, 貴雄
中西, 庸介
近藤, 悟
杉本, 寿史
吉村, 健一
川尻, 秀一
吉崎, 智一
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| 提供者所属 |
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内容記述タイプ |
Other |
|
内容記述 |
金沢大学医薬保健研究域医学系 |
| 書誌情報 |
Acta oto-laryngologica
巻 139,
号 1-2,
p. 94-99,
発行日 2019-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0001-6489 |
| NCID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA0050923X |
| DOI |
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関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1080/00016489.2018.1535193 |
| 出版者 |
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出版者 |
Taylor & Francis |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: In sentinel lymph node (SLN) biopsy for head and neck cancers, the radioisotope method has been the gold standard. However, this method has several problems, such as unavoidable radiation exposure and requirements of expensive equipment. Aims/Objectives: To overcome these problems, we evaluated the contrast-enhanced ultrasonography (CEUS)-guided SLN-detection method, and predicted the SLN metastatic status using novel ultrasound technology, superb microvascular imaging (SMI). Methods: Ten patients (6 with oral and 4 with oropharyngeal cancers) without neck lymph node metastasis were enrolled in this study. Ultrasound contrast agent, Sonazoid ™ , was infiltrated into the mucosa at the primary site to observe the lymphatic ducts and SLNs in the neck field. The detected SLNs were examined for blood flow using SMI to categorize the SLNs metastases-positive or negative. Results: SLNs were successfully detected in 8 out of 10 cases. In 7 out of the 8 cases, in whom SLNs were successfully detected, the metastatic status of SLNs was correctly diagnosed with SMI. Conclusions and significance: Although more clinical data are needed based on a larger cohort, establishing the CEUS-guided SLN-detection and criteria for the accurate diagnosis of SLN-metastases using SMI would be valuable as an alternative to radioisotope method, in oral and oropharyngeal cancers. © 2019, © 2019 Acta Oto-Laryngologica AB (Ltd). |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Embargo Period 12 months |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
# This study was approved by the Bioethics Committee of Kanazawa University (Nos.2016-037 and 2017-015). The clinical study protocol was explained in detail to patients eligible for the study. Written consent was obtained from all patients who agreed to participate.
# This work was supported by a grant-in-aid from The Public Trust Fund For Clinical Cancer Research. |
| 権利 |
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|
権利情報 |
Copyright © 2019 Acta Oto-Laryngologica AB (Ltd). |
| 著者版フラグ |
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出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1535193 |
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|
関連名称 |
https://www.tandfonline.com/doi/full/10.1080/00016489.2018.1535193 |
ME-PR-WAKISAKA-N-94.pdf (423.0 kB)
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