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Enhancement patterns of pancreatic adenocarcinoma on conventional dynamic multi-detector row CT: Correlation with angiogenesis and fibrosis
https://doi.org/10.24517/00061733
https://doi.org/10.24517/00061733b2afb5fc-e2af-49ba-8466-30dd6516d28a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-NAKANUMA-Y-15-3114.pdf (1.1 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2021-08-30 | |||||
| タイトル | ||||||
| タイトル | Enhancement patterns of pancreatic adenocarcinoma on conventional dynamic multi-detector row CT: Correlation with angiogenesis and fibrosis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| ID登録 | ||||||
| ID登録 | 10.24517/00061733 | |||||
| ID登録タイプ | JaLC | |||||
| 著者 |
Hattori, Yuki
× Hattori, Yuki× Gabata, Toshifumi× Matsui, Osamu× Mochizuki, Kentaro× Kitagawa, Hirohisa× Kayahara, Masato× Ohta, Tetsuo× Nakanuma, Yasuni |
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| 著者別名 |
蒲田, 敏文
× 蒲田, 敏文× 松井, 修× 北川, 裕久× 萱原, 正都× 太田, 哲生× 中沼, 安二 |
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| 提供者所属 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 金沢大学医薬保健研究域医学系 | |||||
| 書誌情報 |
World Journal of Gastroenterology 巻 15, 号 25, p. 3114-3121, 発行日 2009 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1007-9327 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA12048247 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3748/wjg.15.3114 | |||||
| 出版者 | ||||||
| 出版者 | Baishideng Publishing Group Co | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Aim: To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. Methods: Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative enhanced value that was calculated by subtracting the attenuation value on pre-contrast from those on contrast-enhanced CT in each phase, we defined one parameter, "tumor-aorta enhancement ratio", which was calculated by dividing enhancement of pancreatic cancer by enhancement of abdominal aorta in each phase. These enhancement patterns were correlated with the level of vascular endothelial growth factor (VEGF), microvessel density (MVD), and extent of fibrosis. Results: The absolute enhanced value in the arterial phase correlated with the level of VEGF and MVD (P = 0.047, P = 0.001). The relative enhanced value in arterial phase and tumor-aorta enhancement ratio (arterial) correlated with MVD (P = 0.003, P = 0.022). Tumor-aorta enhancement ratio (arterial) correlated negatively with the extent of fibrosis (P = 0.004). The tumors with greater MVD and higher expression of VEGF tended to show high enhancement in the arterial dominant phase. On the other hand, the tumors with a larger amount of fibrosis showed a negative correlation with the grade of enhancement during the arterial phase. Conclusion: Enhancement patterns on dynamic CT correlated with angiogenesis and may be modified by the extent of fibrosis. © 2009 The WJG Press and Baishideng. All rights reserved. | |||||
| 権利 | ||||||
| 権利情報 | Copyright ©The Author(s). 2009 Published by Baishideng Publishing Group Inc. All rights reserved. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.wjgnet.com/ | |||||
| 関連名称 | https://www.wjgnet.com/ | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.wjgnet.com/1007-9327/index.htm | |||||
| 関連名称 | https://www.wjgnet.com/1007-9327/index.htm | |||||
