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Autologous serum and serum components
https://doi.org/10.24517/00062809
https://doi.org/10.24517/000628091d3b1823-515c-46ef-a480-7c424604dd33
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
FR-PR-HIGUCHI-A-121.pdf (679.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2021-07-05 | |||||||
| タイトル | ||||||||
| タイトル | Autologous serum and serum components | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| ID登録 | ||||||||
| ID登録 | 10.24517/00062809 | |||||||
| ID登録タイプ | JaLC | |||||||
| 著者 |
Higuchi, Akihiro
× Higuchi, Akihiro |
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| 著者別表示 |
樋口, 明弘
× 樋口, 明弘
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| 提供者所属 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 金沢大学先端科学・社会共創推進機構 | |||||||
| 書誌情報 |
Investigative Ophthalmology and Visual Science 巻 59, 号 14 Special Issue, p. DES121-DES129, 発行日 2018-11 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0146-0404 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 1552-5783 | |||||||
| NCID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00223350 | |||||||
| DOI | ||||||||
| 関連タイプ | isIdenticalTo | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | 10.1167/iovs.17-23760 | |||||||
| 出版者 | ||||||||
| 出版者 | Association for Research in Vision and Ophthalmology Inc. | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Dry eye syndrome is a multifactorial condition on the tear and ocular surface. Autologous serum eye drop is an effective method for treating dry eye. Autologous serum eye drops are now widely used by specialists since a first report in 1975. The results of a systematic study showed that the efficacy of autologous serum eye drops remains ambiguous because its preparation methods and clinical application have not been standardized. To elucidate the efficacy of autologous serum eye drops, well-designed, large-scale, high-quality randomized controlled trials need to be conducted with standardized treatment and use. Since serum components are partially similar to tear components, autologous serum eye drops improve dry eye by supplying tear components such as growth factors, proteins, and vitamins. Adding to the evidence based on the treatment of dry eye, we have found a new treatment candidate from serum: selenoprotein P (SeP). The efficacy of SeP as a treatment for dry eye was revealed by applying SeP eye drops to a dry eye rat model. Compared with phosphate-buffered saline treatment, SeP eye drops significantly reduced the fluorescein score of the cornea and suppressed the oxidative stress in the cornea, which is related to onset of dry eye, leading to improved corneal disorder. We have developed a new dry eye model caused by oxidative stress that will be used to screen candidate molecules for antioxidative activity. © 2018 The Authors. | |||||||
| 権利 | ||||||||
| 権利情報 | Copyright © Association for Research in Vision and Ophthalmology | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 関連URI | ||||||||
| 識別子タイプ | URI | |||||||
| 関連識別子 | http://www.iovs.org/ | |||||||
| 関連名称 | http://www.iovs.org/ | |||||||
| 関連URI | ||||||||
| 識別子タイプ | URI | |||||||
| 関連識別子 | https://iovs.arvojournals.org/article.aspx?articleid=2717222 | |||||||
| 関連名称 | https://iovs.arvojournals.org/article.aspx?articleid=2717222 | |||||||
