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Predictors of exercise-induced oxygen desaturation in systemic sclerosis patients with interstitial lung disease
https://doi.org/10.24517/00064882
https://doi.org/10.24517/0006488289686531-f080-4777-8724-9596c0f82ec1
| 名前 / ファイル | ライセンス | アクション |
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ME-PR-SOMEYA-F-59-75.pdf (376.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2022-02-03 | |||||||||
| タイトル | ||||||||||
| タイトル | Predictors of exercise-induced oxygen desaturation in systemic sclerosis patients with interstitial lung disease | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.24517/00064882 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| 著者 |
Someya, Fujiko
× Someya, Fujiko× Mugii, Naoki× Hasegawa, Minoru× Yahata, Tetsutarou× Nakagawa, Takao |
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| 著者別表示 |
染矢, 富士子
× 染矢, 富士子
× 麦井, 直樹
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| 提供者所属 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 金沢大学医薬保健研究域保健学系 | |||||||||
| 書誌情報 |
Respiratory Care 巻 59, 号 1, p. 75-80, 発行日 2014-01 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0020-1324 | |||||||||
| NCID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA00816862 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.4187/respcare.02452 | |||||||||
| 出版者 | ||||||||||
| 出版者 | American Association for Inhalation Therapy | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Background: The diffusion capacity of the lung for carbon monoxide (DLCO) is a good marker of disease severity in patients with idiopathic interstitial pneumonia, and is associated with oxygen saturation; however, little is known about DLCO in systemic sclerosis patients with interstitial lung disease. We studied potential predictors of exercise-induced oxygen desaturation in patients with systemic sclerosis. Methods: Data were collected prospectively from 80 of 110 consecutive systemic sclerosis patients with normal oxygen saturation (> 95%) at rest, who could perform the 6-min walk test without physical discomfort, including leg pain. Pulmonary function tests and echocardiography were collected from all subjects. Results: Thirty subjects showed a ≥ 4% decline in oxygen saturation during the 6-min walk test (desaturation group). The other subjects were assigned to the normoxic group. The percent-of-predicted values for FVC, FEV1, total lung capacity, DLCO, and DLCO/alveolar volume were lower, and FEV1/FVC was higher, in the desaturation group. Logistic regression analysis showed the percent-of-predicted DLCO as a highly accurate predictor of exercise-induced oxygen desaturation: the area under the receiver operating characteristic curve was 0.92 (cutoff point 56.3%, sensitivity 0.83, specificity 0.86). Five subjects over the cutoff point of the percent-of-predicted DLCO in the desaturation group could not be distinguished from the normoxic subjects with the lung-volume measurements or right-ventricular systolic pressure. Conclusions: The factor underlying exercise-induced oxygen desaturation appeared to be reduced percent-of-predicted DLCO, which was useful as a predictor in over 80% of the subjects. © 2014 Daedalus Enterprises. | |||||||||
| 権利 | ||||||||||
| 権利情報 | Copyright © 2014 Daedalus Enterprises, published by the American Association for Inhalation Therapy | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 関連URI | ||||||||||
| 識別子タイプ | URI | |||||||||
| 関連識別子 | http://rc.rcjournal.com/ | |||||||||
| 関連名称 | http://rc.rcjournal.com/ | |||||||||
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| 識別子タイプ | URI | |||||||||
| 関連識別子 | http://rc.rcjournal.com/content/59/1/75 | |||||||||
| 関連名称 | http://rc.rcjournal.com/content/59/1/75 | |||||||||
