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Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model
https://doi.org/10.24517/00066961
https://doi.org/10.24517/000669615537c426-0e25-4400-b634-47a1385fae9b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
2434-1509-46-1-39-47.pdf (1.3 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2022-08-05 | |||||
| タイトル | ||||||
| タイトル | Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model | |||||
| タイトル | ||||||
| タイトル | Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | rat | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | joint immobilization | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | range of motion exercise | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | myofibroblast | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| ID登録 | ||||||
| ID登録 | 10.24517/00066961 | |||||
| ID登録タイプ | JaLC | |||||
| その他のタイトル | ||||||
| その他のタイトル | 関節可動域運動はラット関節拘縮モデルにおける関節包の筋線維芽細胞増生を抑制する | |||||
| 著者 |
Matsuzaki, Taro
× Matsuzaki, Taro× Yoshida, Shinya× Hoso, Masahiro |
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| 著者別表示 |
松﨑, 太郎
× 松﨑, 太郎× 吉田, 信也× 細, 正博 |
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| 書誌情報 |
Journal of wellness and health care en : Journal of wellness and health care 巻 46, 号 1, p. 39-47, 発行日 2022-08-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2434-1509 | |||||
| 出版者 | ||||||
| 出版者 | Wellness and Health Care Society | |||||
| 出版者（別名） | ||||||
| 出版者 | ウェルネス・ヘルスケア学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objective: Immobilization of the rat knee joint causes fibrosis of the joint capsule, and myofibroblasts have been implicated as the cause. This study aimed to perform range of motion exercises on a rat knee joint contracture model and clarify changes in the joint range of motion and changes in the joint capsule using α -SMA-positive cells. Subjects and Methods: Eighteen male Wistar rats were used and randomly divided into the following three groups: control, immobilized, and exercise. The right hindlimb knee joints of rats in the immobilized and exercise groups were immobilized with external fixation at 120 degrees of flexion, and range of motion exercises were started for the animals in the exercise group the day after the joint immobilization. After a two-week experimental period, the knee joint extension restriction angles were measured, and the knee joints were collected as specimens. To observe the posterior joint capsules of the rat knee joints, hematoxylin and eosin staining and double immunostaining for α -SMA and CD34 were performed. Results: Differences in knee extension restriction angles were significant between all groups, and differences in the number of α -SMA-positive cells were significant between the control and immobilization groups. Conclusion: These results suggest that joint immobilization leads to the proliferation of myofibroblasts, and that range-of-motion exercises may inhibit the proliferation of myofibroblasts. |
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| 権利 | ||||||
| 権利情報 | ウェルネス・ヘルスケア学会 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 見出し | ||||||
| 大見出し | 原著 | |||||
| 言語 | ja | |||||
| 見出し | ||||||
| 大見出し | Original Article | |||||
| 言語 | en | |||||
