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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 20. 紀要
  3. Journal of wellness and health care
  4. Vol.46 No.1 (2022)

Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model

https://doi.org/10.24517/00066961
https://doi.org/10.24517/00066961
5537c426-0e25-4400-b634-47a1385fae9b
名前 / ファイル ライセンス アクション
2434-1509-46-1-39-47.pdf 2434-1509-46-1-39-47.pdf (1.3 MB)
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Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2022-08-05
タイトル
タイトル Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model
タイトル
タイトル Range of motion exercise suppresses myofibroblast proliferation in the joint capsule in a rat joint contracture model
言語 en
言語
言語 eng
キーワード
言語 en
主題Scheme Other
主題 rat
キーワード
言語 en
主題Scheme Other
主題 joint immobilization
キーワード
言語 en
主題Scheme Other
主題 range of motion exercise
キーワード
言語 en
主題Scheme Other
主題 myofibroblast
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
ID登録
ID登録 10.24517/00066961
ID登録タイプ JaLC
その他のタイトル
その他のタイトル 関節可動域運動はラット関節拘縮モデルにおける関節包の筋線維芽細胞増生を抑制する
著者 Matsuzaki, Taro

× Matsuzaki, Taro

WEKO 106462

Matsuzaki, Taro

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Yoshida, Shinya

× Yoshida, Shinya

WEKO 106463

Yoshida, Shinya

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Hoso, Masahiro

× Hoso, Masahiro

WEKO 106464

Hoso, Masahiro

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著者別表示 松﨑, 太郎

× 松﨑, 太郎

WEKO 106465

松﨑, 太郎

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吉田, 信也

× 吉田, 信也

WEKO 106466

吉田, 信也

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細, 正博

× 細, 正博

WEKO 106467

細, 正博

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書誌情報 Journal of wellness and health care
en : Journal of wellness and health care

巻 46, 号 1, p. 39-47, 発行日 2022-08-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 2434-1509
出版者
出版者 Wellness and Health Care Society
出版者(別名)
出版者 ウェルネス・ヘルスケア学会
抄録
内容記述タイプ Abstract
内容記述 Objective: Immobilization of the rat knee joint causes fibrosis of the joint capsule, and
myofibroblasts have been implicated as the cause. This study aimed to perform range of
motion exercises on a rat knee joint contracture model and clarify changes in the joint
range of motion and changes in the joint capsule using α -SMA-positive cells.
Subjects and Methods: Eighteen male Wistar rats were used and randomly divided into
the following three groups: control, immobilized, and exercise. The right hindlimb knee
joints of rats in the immobilized and exercise groups were immobilized with external
fixation at 120 degrees of flexion, and range of motion exercises were started for the
animals in the exercise group the day after the joint immobilization. After a two-week
experimental period, the knee joint extension restriction angles were measured, and the
knee joints were collected as specimens. To observe the posterior joint capsules of the rat
knee joints, hematoxylin and eosin staining and double immunostaining for α -SMA and
CD34 were performed.
Results: Differences in knee extension restriction angles were significant between all
groups, and differences in the number of α -SMA-positive cells were significant between
the control and immobilization groups.
Conclusion: These results suggest that joint immobilization leads to the proliferation
of myofibroblasts, and that range-of-motion exercises may inhibit the proliferation of
myofibroblasts.
権利
権利情報 ウェルネス・ヘルスケア学会
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
見出し
大見出し 原著
言語 ja
見出し
大見出し Original Article
言語 en
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