| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2023-05-08 |
| タイトル |
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|
タイトル |
Triexponential Diffusion Analysis of Diffusion-weighted Imaging for Breast Ductal Carcinoma in Situ and Invasive Ductal Carcinoma |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.24517/00069505 |
|
ID登録タイプ |
JaLC |
| 著者 |
Ohno, Masako
Ohno, Naoki
Miyati, Tosiaki
Kawashima, Hiroko
Kozaka, Kazuto
Matsuura, Yukihiro
Gabata, Toshifumi
Kobayashi, Satoshi
|
| 著者別表示 |
大野, 雅子
大野, 直樹
宮地, 利明
川島, 博子
小坂, 一斗
松浦, 幸広
蒲田, 敏文
小林, 聡
|
| 提供者所属 |
|
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内容記述タイプ |
Other |
|
内容記述 |
金沢大学附属病院放射線部 |
| 書誌情報 |
Magnetic resonance in medical sciences
巻 20,
号 4,
p. 396-403,
発行日 2021-02-09
|
| ISSN |
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|
収録物識別子タイプ |
ISSN |
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収録物識別子 |
1347-3182 |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1880-2206 |
| NCID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11648770 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.2463/mrms.mp.2020-0103 |
| 出版者 |
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出版者 |
日本磁気共鳴医学会 Japanese Society for Magnetic Resonance in Medicine |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: To obtain detailed information in breast ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) using triexponential diffusion analysis.
Methods: Diffusion-weighted images (DWI) of the breast were obtained using single-shot diffusion echo-planar imaging with 15 b-values. Mean signal intensities at each b-value were measured in the DCIS and IDC lesions and fitted with the triexponential function based on a two-step approach: slow-restricted diffusion coefficient (Ds) was initially determined using a monoexponential function with b-values > 800 s/mm2. The diffusion coefficient of free water at 37°C was assigned to the fast-free diffusion coefficient (Df). Finally, the perfusion-related diffusion coefficient (Dp) was derived using all the b-values. Furthermore, biexponential analysis was performed to obtain the perfusion-related diffusion coefficient (D*) and the perfusion-independent diffusion coefficient (D). Monoexponential analysis was performed to obtain the apparent diffusion coefficient (ADC). The sensitivity and specificity of the aforementioned diffusion coefficients for distinguishing between DCIS and IDC were evaluated using the pathological results.
Results: The Ds, D, and ADC of DCIS were significantly higher than those of IDC (P < 0.01 for all). There was no significant correlation between Dp and Ds, but there was a weak correlation between D* and D. The combination of Dp and Ds showed higher sensitivity and specificity (85.9% and 71.4%, respectively), compared to the combination of D* and D (81.5% and 33.3%, respectively).
Conclusion: Triexponential analysis can provide detailed diffusion information for breast tumors that can be used to differentiate between DCIS and IDC. |
| 権利 |
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|
権利情報 |
Copyright ©2021 Japanese Society for Magnetic Resonance in Medicine |
| 権利 |
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|
権利情報 |
CC BY-NC-ND 4.0 |
| 著者版フラグ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://www.jstage.jst.go.jp/browse/mrms/-char/en |
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関連名称 |
https://www.jstage.jst.go.jp/browse/mrms/-char/en |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://www.jsmrm.jp/modules/mrms/index.php?content_id=1 |
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関連名称 |
https://www.jsmrm.jp/modules/mrms/index.php?content_id=1 |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://www.jsmrm.jp/ |
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|
関連名称 |
https://www.jsmrm.jp/ |
ME-PR-OHNO-M-20-396.pdf (1.2 MB)
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