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  1. C. 理工学域; 数物科学類・物質化学類・機械工学類・フロンティア工学類・電子情報通信学類・地球社会基盤学類・生命理工学類
  2. c 10. 学術雑誌掲載論文
  3. 1.査読済論文(工)

ヒト血清アルブミンリン酸緩衝溶液の近赤外領域における分光学的特性およびその定量化の試み

http://hdl.handle.net/2297/28487
http://hdl.handle.net/2297/28487
28818966-c3ce-4cd7-b351-e0a2ee25b985
名前 / ファイル ライセンス アクション
TE-PR-YAMAKOSHI-T-259.pdf TE-PR-YAMAKOSHI-T-259.pdf (4.6 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-03
タイトル
タイトル ヒト血清アルブミンリン酸緩衝溶液の近赤外領域における分光学的特性およびその定量化の試み
タイトル
言語 en
タイトル Near-infrared spectroscopy of human serum albumin and determination of its concentrations in phosphate buffer solutions
言語
言語 jpn
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 小川, 充洋

× 小川, 充洋

WEKO 1064
研究者番号 30322085

小川, 充洋

Search repository
山越, 健弘

× 山越, 健弘

WEKO 14139
研究者番号 46033528

山越, 健弘

Search repository
田中, 志信

× 田中, 志信

WEKO 78
e-Rad 40242218
金沢大学研究者情報 40242218
研究者番号 40242218

田中, 志信

Search repository
山越, 憲一

× 山越, 憲一

WEKO 42
e-Rad 40014310
研究者番号 40014310

山越, 憲一

Search repository
書誌情報 生体医工学 : 日本エム・イー学会誌 = Transactions of the Japanese Society for Medical and Biological Engineering

巻 48, 号 3, p. 259-268, 発行日 2010-06-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 1347-443X
NCID
収録物識別子タイプ NCID
収録物識別子 AA11633569
出版者
出版者 日本生体医工学会 = Japanese Society for medical and Bilogical Engineering
抄録
内容記述タイプ Abstract
内容記述 Near-infrared differential absorbance spectra from pure water have been measured for phosphate buffer solutions (pH = 7.4) of human serum albumin (HSA) in the wavelength range of 750-2500nm. The peaks that follow HSA concentration can be observed in near-infrared differential absorbance spectra; in the 1650-1750nm and 2150-2350nm region. The near-infrared spectra in the 750-1350nm, 1550-1850nm and 2052-2500nm regions of the solutions have been subjected to partial least squares (PLS) regression analysis to make calibration models predicting the concentrations of the HSA. The calibration in the concentration range of 0-5g/dl has yielded a correlation coefficient of 0.999 and a standard error of prediction of 0.0283g/dl with latent variable of seven. This result suggests that the near-infrared differential spectra of HSA from pure water reference and its calibration model constructed by using PLS regression can pick up effectively the information about albumin contained in phosphate buffer solutions. This result can be a base of reagentless measurement of HSA in human serum and in vivo HSA measurement.
権利
権利情報 Copyright (c) 2011 社団法人日本生体医工学会
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85