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A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus
https://doi.org/10.24517/00062679
https://doi.org/10.24517/000626798975eb0c-3d2c-4644-9f59-2cf50ee45bd6
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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公開日 | 2021-06-28 | |||||||
タイトル | ||||||||
タイトル | A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus | |||||||
言語 | ||||||||
言語 | eng | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | journal article | |||||||
ID登録 | ||||||||
ID登録 | 10.24517/00062679 | |||||||
ID登録タイプ | JaLC | |||||||
著者 |
Suzuki, Kensuke
× Suzuki, Kensuke× Nagasaka, Kazunori× Oda, Katsutoshi× abe, Hiroyuki× Maeda, Daichi× Matsumoto, Yoko× Arimoto, Takahide× Kawana, Kei× Fukayama, Masashi× Osuga, Yutaka× Fujii, Tomoyuki |
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著者別表示 |
前田, 大地
× 前田, 大地
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提供者所属 | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||||
書誌情報 |
BMC Cancer 巻 16, 号 1, p. 390, 発行日 2016-07-04 |
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ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 1471-2407 | |||||||
NCID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AA12034763 | |||||||
DOI | ||||||||
関連タイプ | isIdenticalTo | |||||||
識別子タイプ | DOI | |||||||
関連識別子 | 10.1186/s12885-016-2413-z | |||||||
出版者 | ||||||||
出版者 | BioMed Central Ltd. | |||||||
抄録 | ||||||||
内容記述タイプ | Abstract | |||||||
内容記述 | Background: Lymphangioleiomyomatosis (LAM) is a rare idiopathic disorder that occurs in women of childbearing age, and consists of a diffuse proliferation of abnormal smooth muscle cells along the thoracic and abdominal lymphogenous route. Case presentation: We experienced a case of a 47-yo woman with recent history of systemic lupus erythematosus (SLE) diagnosed with endometrial cancer, initially suspected to have metastasized to pelvic and para-aortic lymph nodes based on preoperative diagnostic imaging. Subsequent pathological diagnosis revealed stage IB endometrial cancer without evidence of lymph node involvement. Instead, enlarged pelvic and para-aortic lymph nodes were found to be due to extrapulmonary LAM, from a primary lesion found inside the uterine myometrium. SLE improved after surgery. Conclusion: This is the first reported case of comorbid endometrial cancer, SLE, and aggressive LAM metastasizing to regional lymph nodes, and strengthens the clinical evidence for a common role of mTOR pathway hyperactivity and estrogen responsiveness in the pathophysiology of metastasizing lesions of the genital tract. © 2016 The Author(s). | |||||||
権利 | ||||||||
権利情報 | Copyright © BioMed Central Ltd. | |||||||
著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
関連URI | ||||||||
識別子タイプ | URI | |||||||
関連識別子 | http://www.biomedcentral.com/bmccancer/ | |||||||
関連名称 | http://www.biomedcentral.com/bmccancer/ | |||||||
関連URI | ||||||||
識別子タイプ | URI | |||||||
関連識別子 | https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2413-z | |||||||
関連名称 | https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2413-z |