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A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus
https://doi.org/10.24517/00062679
https://doi.org/10.24517/000626798975eb0c-3d2c-4644-9f59-2cf50ee45bd6
名前 / ファイル | ライセンス | アクション |
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ME-PR-MAEDA-D-390.pdf (1.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2021-06-28 | |||||
タイトル | ||||||
タイトル | A case of lymphangioleiomyomatosis associated with endometrial cancer and severe systemic lupus erythematosus | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00062679 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Suzuki, Kensuke
× Suzuki, Kensuke× Nagasaka, Kazunori× Oda, Katsutoshi× abe, Hiroyuki× Maeda, Daichi× Matsumoto, Yoko× Arimoto, Takahide× Kawana, Kei× Fukayama, Masashi× Osuga, Yutaka× Fujii, Tomoyuki |
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著者別表示 |
前田, 大地
× 前田, 大地 |
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提供者所属 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 金沢大学医薬保健研究域医学系 | |||||
書誌情報 |
BMC Cancer 巻 16, 号 1, p. 390, 発行日 2016-07-04 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1471-2407 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA12034763 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s12885-016-2413-z | |||||
出版者 | ||||||
出版者 | BioMed Central Ltd. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Lymphangioleiomyomatosis (LAM) is a rare idiopathic disorder that occurs in women of childbearing age, and consists of a diffuse proliferation of abnormal smooth muscle cells along the thoracic and abdominal lymphogenous route. Case presentation: We experienced a case of a 47-yo woman with recent history of systemic lupus erythematosus (SLE) diagnosed with endometrial cancer, initially suspected to have metastasized to pelvic and para-aortic lymph nodes based on preoperative diagnostic imaging. Subsequent pathological diagnosis revealed stage IB endometrial cancer without evidence of lymph node involvement. Instead, enlarged pelvic and para-aortic lymph nodes were found to be due to extrapulmonary LAM, from a primary lesion found inside the uterine myometrium. SLE improved after surgery. Conclusion: This is the first reported case of comorbid endometrial cancer, SLE, and aggressive LAM metastasizing to regional lymph nodes, and strengthens the clinical evidence for a common role of mTOR pathway hyperactivity and estrogen responsiveness in the pathophysiology of metastasizing lesions of the genital tract. © 2016 The Author(s). | |||||
権利 | ||||||
権利情報 | Copyright © BioMed Central Ltd. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.biomedcentral.com/bmccancer/ | |||||
関連名称 | http://www.biomedcentral.com/bmccancer/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2413-z | |||||
関連名称 | https://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2413-z |