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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 1. 査読済論文(医学・保健)

Use of self-setting α-tricalcium phosphate for maxillary sinus augmentation in rabbit

http://hdl.handle.net/2297/27799
http://hdl.handle.net/2297/27799
6673804f-a752-44d7-9dab-490c30f3b289
名前 / ファイル ライセンス アクション
ME-PR-UEKI-K-606.pdf ME-PR-UEKI-K-606.pdf (1.4 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-03
タイトル
タイトル Use of self-setting α-tricalcium phosphate for maxillary sinus augmentation in rabbit
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Ueki, Koichiro

× Ueki, Koichiro

WEKO 575
e-Rad 40313663
研究者番号 40313663

Ueki, Koichiro

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Okabe, Katsuhiko

× Okabe, Katsuhiko

WEKO 21932

Okabe, Katsuhiko

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Nakagawa, Kiyomasa

× Nakagawa, Kiyomasa

WEKO 496
研究者番号 30155676

Nakagawa, Kiyomasa

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Yamamoto, Etsuhide

× Yamamoto, Etsuhide

WEKO 157
e-Rad 00092445
金沢大学研究者情報 00092445
研究者番号 00092445

Yamamoto, Etsuhide

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提供者所属
内容記述タイプ Other
内容記述 金沢大学医薬保健研究域医学系
書誌情報 Clinical Oral Implants Research

巻 22, 号 6, p. 606-612, 発行日 2011-06-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 0905-7161
NCID
収録物識別子タイプ NCID
収録物識別子 AA1078090X
DOI
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 10.1111/j.1600-0501.2010.02023.x
出版者
出版者 Wiley-Blackwell
抄録
内容記述タイプ Abstract
内容記述 Purpose: The purpose of this study was to histologically and immuno-histochemically evaluate tissue changes in the maxillary sinus after bone screw implantation and maxillary sinus augmentation using self-setting α-tricalcium phosphate (α-TCP; BIOPEX®-R) in rabbit. Study design: Adult male Japanese white rabbits (n=15, 12-16 weeks, 2.5-3kg) were used. The sinus lift was made from the nasal bone of a rabbit. Bone screws (Dual top auto-screw®) were implanted into the nasal bone, and after BIOPEX®-R was implanted into the left elevated space (operated side) an atelocollagen sponge (ACS: Teruplug®) was implanted into the right elevated space (control side). The rabbits were sacrificed at 4, 12 and 24 weeks postoperatively, and formalin-fixed specimens were embedded in acrylic resin. The specimens were stained with hematoxylin and eosin. For immune-histochemical analysis, the specimens were treated with bone morphogenetic protein-2 (BMP-2) antibodies. Finally, these were evaluated microscopically. Results: Tight bonding without fibrous tissue continued between the bone screw and BIOPEX®-R, and the rigidity of the bone screw in the nasal bone was retained for 24 weeks in all cases. The area ofnew bone formation increased gradually on both sides; however, there was no significant difference between both sides at 4, 12 and 24 weeks. The number of BMP-2-stained cells on the experimental side was significantly larger than that on the control side after 4 weeks (P=0.0361). Conclusion: This study suggested the usefulness of self-setting α-TCP (BIOPEX®-R) to maintain the rigidity of implanted bone screws from an early period, and the result of BMP-2 expression suggested that BIOPEX®-R could have bone-conductive activity in the maxillary sinus augmentation. © 2010 John Wiley & Sons A/S.
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
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