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  1. C. 医薬保健学域; 医学類・薬学類・医薬科学類・保健学類
  2. c 10. 学術雑誌掲載論文(医・保健)
  3. 1. 査読済論文(医学・保健)

Is Estrogen Effective for Full-Thickness Cutaneous Wound Healing in Young Male Mice ?

http://hdl.handle.net/2297/35866
http://hdl.handle.net/2297/35866
27a4cc6e-9056-472f-83c7-3968cb147cb5
名前 / ファイル ライセンス アクション
ME-PR-NAKATANI-T-278.pdf ME-PR-NAKATANI-T-278.pdf (585.1 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2017-10-03
タイトル
タイトル Is Estrogen Effective for Full-Thickness Cutaneous Wound Healing in Young Male Mice ?
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Nakajima, Yukari

× Nakajima, Yukari

WEKO 22514
e-Rad 40846680

Nakajima, Yukari

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Eno, Yuka

× Eno, Yuka

WEKO 22515

Eno, Yuka

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Hirata, Mariko

× Hirata, Mariko

WEKO 22516

Hirata, Mariko

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Kobori, Sawako

× Kobori, Sawako

WEKO 22517

Kobori, Sawako

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Sugiura, Ayano

× Sugiura, Ayano

WEKO 22518

Sugiura, Ayano

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Takeuchi, Maiko

× Takeuchi, Maiko

WEKO 22519

Takeuchi, Maiko

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Taniguchi, Miho

× Taniguchi, Miho

WEKO 22520

Taniguchi, Miho

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Tanisaki, Megumi

× Tanisaki, Megumi

WEKO 22521

Tanisaki, Megumi

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Hayashi, Asuka

× Hayashi, Asuka

WEKO 22522

Hayashi, Asuka

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Hikishima, Keiko

× Hikishima, Keiko

WEKO 22523

Hikishima, Keiko

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Matsuo, Naoki

× Matsuo, Naoki

WEKO 22524

Matsuo, Naoki

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Wada, Natsumi

× Wada, Natsumi

WEKO 22525

Wada, Natsumi

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Mukai, Kanae

× Mukai, Kanae

WEKO 22526
e-Rad 30755335

Mukai, Kanae

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Murakado, Naoko

× Murakado, Naoko

WEKO 197
e-Rad 30303283
研究者番号 30303283

Murakado, Naoko

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Okuwa, Mayumi

× Okuwa, Mayumi

WEKO 140
e-Rad 30303291
金沢大学研究者情報 30303291
研究者番号 30303291

Okuwa, Mayumi

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Nakatani, Toshio

× Nakatani, Toshio

WEKO 223
金沢大学研究者情報 60198124
研究者番号 60198124

Nakatani, Toshio

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書誌情報 Wounds : a compendium of clinical research and practice

巻 25, 号 10, p. 278-286, 発行日 2013-10-15
ISSN
収録物識別子タイプ ISSN
収録物識別子 1044-7946
NCID
収録物識別子タイプ NCID
収録物識別子 AA11196613
出版者
出版者 Health Management Publications
抄録
内容記述タイプ Abstract
内容記述 The aim of this study is to show the effects of estrogen upon its topical application on the wound healing process in young male mice. Fifty-six male mice aged 7 weeks old were divided into 4 groups: sham operation, castration, estrogen treatment after sham operation, and estrogen treatment after castration. Wound healing was observed daily until day 14 after wounding. Specimens were harvested on days 3, 7, 10, and 14, and stained to evaluate reepithelialization, inflammation, contraction, and collagen accumulation. Wound healing periods of all groups were almost the same, although the concentration of serum estrogen in the estrogen-applied mice was very high, and that in the nonapplied groups was low. The numbers of macrophages in the castrated, estrogen-treated after sham operation, and estrogen-treated after castration groups were significantly decreased compared with that in the sham group in the inflammatory phase; however, the ratio of wound area in these groups did not decrease, and other histological data did not reveal any effects of estrogen. These results indicate that estrogen may show limited effectiveness for full-thickness cutaneous wound healing in young male mice, and decreased inflammation may not always be associated with decreased wound area.
著者版フラグ
出版タイプ AM
出版タイプResource http://purl.org/coar/version/c_ab4af688f83e57aa
関連URI
識別子タイプ URI
関連識別子 http://www.woundsresearch.com
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