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No increase of drug-resistant HIV type 1 prevalence among drug-naive individuals in northern vietnam
http://hdl.handle.net/2297/32833
http://hdl.handle.net/2297/3283379de2bd7-919f-4725-a57e-8255925b7af7
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-ISHZAKI-A-1349.pdf (59.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | No increase of drug-resistant HIV type 1 prevalence among drug-naive individuals in northern vietnam | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Tran, Vuong Thi
× Tran, Vuong Thi× Ishizaki, Azumi× Nguyen, Cuong Hung× Hoan, Huyen Thi× Pham, Hung Viet× Bi, Xiuqiong× Pham, Thuc Van× Ichimura, Hiroshi |
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| 書誌情報 |
AIDS Research and Human Retroviruses 巻 28, 号 10, p. 1349-1351, 発行日 2012-10-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0889-2229 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA10689080 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1089/aid.2012.0006 | |||||
| 出版者 | ||||||
| 出版者 | Mary Ann Liebert | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We reported previously that the prevalence of drug-resistant HIV-1 among antiretroviral therapy (ART)-naive individuals in Northern Vietnam was 2.9% in 2007 and 6.2% in 2008. To investigate the continuing trend of prevalence, we collected plasma samples from 958 individuals in Hai Phong and Hanoi in 2009, extracted viral RNA from HIV-1 antibody-positive samples, and analyzed them genetically. HIV-1 antibody prevalence was 26.8% in injecting drug users (n=302), 13.4% in female sex workers (n=284), 0.5% in blood donors (n=206), and 0.6% in pregnant women (n=166). All HIV-1 strains were CRF01-AE. Nonnucleoside reverse-transcriptase inhibitor resistance mutations were found in two (2.0%) of the 102 successfully analyzed cases (one case with the Y181C and one with the K101E). No nucleoside reverse-transcriptase inhibitor resistance or protease inhibitor resistance mutations were detected. The prevalence of circulating ART-resistant HIV-1 in Northern Vietnam did not increase from 2007 to 2009, although the rate of ART coverage did increase. © 2012, Mary Ann Liebert, Inc. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
