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Subzero 24-hr nonfreezing rat heart preservation: A novel preservation method in a variable magnetic field
http://hdl.handle.net/2297/32861
http://hdl.handle.net/2297/328614b5979ed-cadb-4221-b4d9-95c60e22b703
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-KATO-H-473.pdf (421.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Subzero 24-hr nonfreezing rat heart preservation: A novel preservation method in a variable magnetic field | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Kato, Hiroki
× Kato, Hiroki× Tomita, Shigeyuki× Yamaguchi, Shoujiro× Ohtake, Hiroshi× Watanabe, Go |
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| 書誌情報 |
Transplantation 巻 94, 号 5, p. 473-477, 発行日 2012-09-15 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0041-1337 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00868935 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1097/TP.0b013e3182637054 | |||||
| 出版者 | ||||||
| 出版者 | Lippincott, Williams & Wilkins | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | BACKGROUND: A new supercooling system using a variable magnetic field has been recently developed. Subzero nonfreezing preservation has been believed to be a beneficial method because of the lower metabolic rate. The purpose of this study was to evaluate the hemodynamic and metabolic effects of rat heart preservation in a variable magnetic field without cryoprotectants. METHODS: Rat hearts were perfused ex vivo for 120 min after 24-hr preservation in two groups (n=6 each): (1) conventional storage group, in which the hearts were stored at 4°C, and (2) the subzero group, in which the hearts were preserved at-3°C in a variable magnetic field. RESULTS: Reperfusion cardiac performance after preservation was significantly preserved in the subzero group compared with the conventional group with respect to heart rate, coronary flow, the peak positive dP/dt, and the peak negative dP/dt (P<0.05). Edema after reperfusion was significantly decreased (P<0.05), and the adenosine triphosphate level was higher in the subzero group (P<0.05). CONCLUSIONS: The rat hearts preserved in a variable magnetic field at-3°C showed better hemodynamic and metabolic performance than those preserved using conventional storage at 4°C. Copyright © 2012 Lippincott Williams &Wilkins. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
