{"_buckets": {"deposit": "4e006647-8f1c-45bd-a64d-0a787235ccff"}, "_deposit": {"created_by": 3, "id": "14191", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "14191"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00014191", "sets": ["1134"]}, "author_link": ["15392", "259"], "item_11_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-09-04", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "the series Neuromethods", "bibliographicPageEnd": "127", "bibliographicPageStart": "109", "bibliographicVolumeNumber": "108", "bibliographic_titles": [{"bibliographic_title": "Designer Receptors Exclusively Activated by Designer Drugs"}]}]}, "item_11_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Sleep and wakefulness are controlled by a complex network of neurons harboring diverse neurochemical characteristics, including glutamatergic, GABAergic, monoaminergic, cholinergic, and peptidergic neurons. To understand the precise role of each type of neuron in this circuit, it is useful to artificially manipulate the activity of a particular type of neuron to see its effect on behavior. The DREADD system has made such a strategy possible. Here, we review our recent work using DREADD to pharmacogenetically dissect neural mechanisms regulating sleep-wakefulness, describe the protocol we used, and discuss the technical aspects of our studies. © Springer Science+Business Media New York 2015. All rights reserved.", "subitem_description_type": "Abstract"}]}, "item_11_description_22": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "Book Chapter, Embargo Period 12 months", "subitem_description_type": "Other"}]}, "item_11_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Springer Science+Business Media"}]}, "item_11_relation_10": {"attribute_name": "ISBN", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "978-149392944-3", "subitem_relation_type_select": "ISBN"}}, {"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "978-149392943-6", "subitem_relation_type_select": "ISBN"}}]}, "item_11_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/978-1-4939-2944-3_7", "subitem_relation_type_select": "DOI"}}]}, "item_11_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Mieda, Michihiro"}], "nameIdentifiers": [{"nameIdentifier": "259", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "20296552", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=20296552"}, {"nameIdentifier": "20296552", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20296552"}, {"nameIdentifier": "20296552", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000020296552"}]}, {"creatorNames": [{"creatorName": "Sakurai, Takeshi"}], "nameIdentifiers": [{"nameIdentifier": "15392", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60251055", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60251055"}, {"nameIdentifier": "60251055", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000060251055"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-MIEDA-M-109.pdf", "filesize": [{"value": "471.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 471300.0, "url": {"label": "ME-PR-MIEDA-M-109.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/14191/files/ME-PR-MIEDA-M-109.pdf"}, "version_id": "6d5e9f64-2391-4d60-b7f3-7b6b05c90b38"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Hypothalamus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Narcolepsy", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Neuropeptide", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Orexin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Preoptic area", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Sleep-wakefulness", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Transgenic mice", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "book", "resourceuri": "http://purl.org/coar/resource_type/c_2f33"}]}, "item_title": "Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs"}]}, "item_type_id": "11", "owner": "3", "path": ["1134"], "permalink_uri": "http://hdl.handle.net/2297/44892", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "14191", "relation": {}, "relation_version_is_last": true, "title": ["Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs"], "weko_shared_id": 3}