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Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs
http://hdl.handle.net/2297/44892
http://hdl.handle.net/2297/448928626ccfc-db9d-404e-8eb4-9dad66eba53b
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-MIEDA-M-109.pdf (471.3 kB)
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| Item type | 図書 / Book(1) | |||||
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| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Pharmacogenetic dissection of neural mechanisms underlying the regulation of sleep-wakefulness using DREADDs | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_2f33 | |||||
| 資源タイプ | book | |||||
| 著者 |
Mieda, Michihiro
× Mieda, Michihiro× Sakurai, Takeshi |
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| 書誌情報 |
Designer Receptors Exclusively Activated by Designer Drugs 巻 108, 号 the series Neuromethods, p. 109-127, 発行日 2015-09-04 |
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| ISBN | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | ISBN | |||||
| 関連識別子 | 978-149392944-3 | |||||
| ISBN | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | ISBN | |||||
| 関連識別子 | 978-149392943-6 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/978-1-4939-2944-3_7 | |||||
| 出版者 | ||||||
| 出版者 | Springer Science+Business Media | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Sleep and wakefulness are controlled by a complex network of neurons harboring diverse neurochemical characteristics, including glutamatergic, GABAergic, monoaminergic, cholinergic, and peptidergic neurons. To understand the precise role of each type of neuron in this circuit, it is useful to artificially manipulate the activity of a particular type of neuron to see its effect on behavior. The DREADD system has made such a strategy possible. Here, we review our recent work using DREADD to pharmacogenetically dissect neural mechanisms regulating sleep-wakefulness, describe the protocol we used, and discuss the technical aspects of our studies. © Springer Science+Business Media New York 2015. All rights reserved. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Book Chapter, Embargo Period 12 months | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
