WEKO3
インデックスリンク
アイテム
Increased level of tumour necrosis factor-alpha (TNF-α) on the skin of Japanese obese males: Measured by quantitative skin blotting
https://doi.org/10.24517/00014384
https://doi.org/10.24517/000143844b57075f-6a88-465f-b79f-006c8d0e50ca
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ME-PR-OGAI-K-462.pdf (618.1 kB)
|
.png)
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2017-10-03 | |||||||||
| タイトル | ||||||||||
| タイトル | Increased level of tumour necrosis factor-alpha (TNF-α) on the skin of Japanese obese males: Measured by quantitative skin blotting | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.24517/00014384 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| 著者 |
Ogai, Kazuhiro
× Ogai, Kazuhiro× Matsumoto, M.× Aoki, M.× Minematsu, Takeo× Kitamura, K.× Kobayashi, M.× Sanada, H.× Sugama, Junko |
|||||||||
| 著者別表示 |
大貝, 和裕
× 大貝, 和裕
× 須釜, 淳子
|
|||||||||
| 書誌情報 |
International Journal of Cosmetic Science 巻 38, 号 5, p. 462-469, 発行日 2016-10-01 |
|||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0142-5463 | |||||||||
| NCID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA00234029 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.1111/ics.12312 | |||||||||
| 出版者 | ||||||||||
| 出版者 | Blackwell Publishing Ltd | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Objective: A state of chronic inflammation, characterized by an increased level of tumour necrosis factor-alpha (TNF-α), is often found in the obese population. The negative effects of elevated TNF-α are not limited to systemic metabolism. It also reportedly affects skin integrity. Recently, the relationship between obesity and skin fragility was reported; however, there has been little insight into how the level of TNF-α in the skin in situ is related to the severity of obesity. In this study, we aimed to measure the level of TNF-α on the skin and to find the relationship between obesity and the level of TNF-α detected on the skin. Methods: We used a novel, non-invasive method called quantitative skin blotting. Fifty-nine healthy (but some were classified as being overweight or obese) Japanese males were enrolled as subjects. The levels of TNF-α detected on the abdominal and thigh skin along with the body composition were measured, followed by a correlation analysis. Results: Significant positive correlations were found between the levels of TNF-α detected on the skin and the severity of obesity such as body mass index (BMI), body fat weight and visceral fat rating. Conclusion: We found that high levels of TNF-α were detected on the skin of Japanese obese males, which implied the higher TNF-α in the skin. The elevation of skin TNF-α may be one factor related to skin fragility that is often found in obese individuals. © 2016 John Wiley & Sons Ltd. | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Embargo Period 12 months | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
