{"_buckets": {"deposit": "8a8e592e-2eac-4e4f-b710-14d802349d45"}, "_deposit": {"created_by": 3, "id": "14506", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "14506"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00014506", "sets": ["1134"]}, "author_link": ["20086", "25479", "25477", "25476", "25478", "25475", "25473", "25474"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-01-22", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "6", "bibliographicPageStart": "1", "bibliographicVolumeNumber": "47", "bibliographic_titles": [{"bibliographic_title": "日本臨床細胞学会雑誌"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "目的: 子宮頸がん検診に従来の細胞診に HPV 検査を導入することの有用性を検討した. 方法: ベセスダシステム (2001) で意義不明の異型扁平上皮細胞を ASC と分類している. 平成 16∼18 年の 3 年間の金沢市民を対象にした行政の子宮頸がん検診において, ASC (ASC-US と ASC-H) 例にハイブリッドキャプチャー 2 (HC2) で高リスク型 HPV の検査を併用し, HPV 陽性例と軽度異形性以上の病変を推定した例にコルポスコープ下の組織検査を行い, HPV 検査導入前の 3 年間と比較検討した. 成績: 3 年間の金沢市の子宮頸がん検診受診者 3 万 3790 人中 ASC は 1565 人 (4.6%) で, そのうち 221 例 (14.1%) が HPV 陽性であった. 221 例中精検受診者は 169 例 (76.5%) で, そのなかから CIN2 以上が 27 例検出された. 浸潤がんは認めなかった. 結論: 細胞診で判定の難しい ASC 例に対し, HPV 検査を導入することによって感度が高められ, 見逃しを減らすと同時に, 不必要な生検を省くことができると考えられる. Objectives: Human papillomavirus (HPV) DNA testing was done as an adjunct to cervical cytology to evaluate its usefulness in cervical cancer screening. Study Design: Between May 2004 and March 2006, 33790 women living in Kanazawa City were screened based on Bethesda cytological classification. In cases with ASC (ASC-US and ASC-H), HPV DNA testing was done using Hybrid Capture-II. Cytology-ASC-and HPV-positive women underwent colposcopy to determine the histological diagnosis. Results: Of these 33790, 1565 (4.6%) had ASC cytology. HPV DNA was positive in 221 (14.1%) of the 1565. Of these 221, 169 (76.5%) underwent biopsy. Of these 169, 27 had disease exceeding CIN 2. Conclusions: HPV DNA testing, combined with cytology significantly improved CIN screening efficacy and avoided unnecessary biopsies.", "subitem_description_type": "Abstract"}]}, "item_4_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学医薬保健研究域医学系", "subitem_description_type": "Other"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本臨床細胞学会雑誌 = The Japanese Society of Clinical Cytology"}]}, "item_4_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://japanlinkcenter.org/JST.JSTAGE/jjscc/47.1", "subitem_relation_type_select": "URI"}}, {"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://www.jscc.or.jp/index.html", "subitem_relation_type_select": "URI"}}, {"subitem_relation_type_id": {"subitem_relation_type_id_text": "http://ci.nii.ac.jp/naid/110006571287", "subitem_relation_type_select": "URI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright (c) 2008 特定非営利活動法人 日本臨床細胞学会"}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00198721", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0387-1193", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "丹後, 正紘"}], "nameIdentifiers": [{"nameIdentifier": "25473", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "金谷, 太郎"}], "nameIdentifiers": [{"nameIdentifier": "25474", "nameIdentifierScheme": 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