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Studies on Metabolites of Macrophoma commelinae. IV. : Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids
http://hdl.handle.net/2297/33670
http://hdl.handle.net/2297/33670a1b94376-07b3-44c1-9754-000f198d7799
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PH-PR-SHIMIZU-S-2003.pdf (1.0 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-04 | |||||
| タイトル | ||||||
| タイトル | Studies on Metabolites of Macrophoma commelinae. IV. : Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Sakurai, Ikuo
× Sakurai, Ikuo× Miyajima, Hisae× Akiyama, Katsuyoshi× Shimizu, Sakae× Yamamoto, Yuzuru |
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| 書誌情報 |
Chemical & pharmaceutical bulletin 巻 36, 号 6, p. 2003-2011, 発行日 1988-06-25 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0009-2363 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00602100 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/cpb.36.2003 | |||||
| 出版者 | ||||||
| 出版者 | 日本薬学会 Pharmaceutical Society of Japan | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Substrate specificity in the novel biotransformation from 2-pyrone derivatives to substituted benzoic acids by Macrophoma commelinae (IFO 9570) was investigated by means of feeding experiments with various compounds. Among them, 2-pyrone derivatives substituted by an electron-donating group at C-4,by an electron-withdrawing group at C-5 and by an alkyl group at C-6 were converted to the corresponding benzoic acid derivatives in fairly good yields. The C_3-unit precursors and intermediates were examined in stationary or shaking culture. Based on the experimental results obtained, a mechanism for this unique reaction is proposed. | |||||
| 権利 | ||||||
| 権利情報 | Copyright © The Pharmaceutical Society of Japan | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://ci.nii.ac.jp/naid/110003627029/ | |||||
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| 識別子タイプ | URI | |||||
| 関連識別子 | https://japanlinkcenter.org/JST.Journalarchive/cpb1958/36.2003 | |||||
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| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/article/cpb1958/36/6/36_6_2003/_article | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.pharm.or.jp/ | |||||
