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Antitumor Activity of Asterriquinones from Aspergillus Fungi. IV. An Attempt to modify the Structure of Asterriquinones to increase the Activity
http://hdl.handle.net/2297/34354
http://hdl.handle.net/2297/343543e33c9ef-92ea-468c-9ef8-c48d48e7e111
名前 / ファイル | ライセンス | アクション |
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PH-PR-SHIMIZU-S-1896.pdf (470.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-04 | |||||
タイトル | ||||||
タイトル | Antitumor Activity of Asterriquinones from Aspergillus Fungi. IV. An Attempt to modify the Structure of Asterriquinones to increase the Activity | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shimizu, Sakae
× Shimizu, Sakae× Yamamoto, Yuzuru× Koshimura, Saburo |
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書誌情報 |
Chemical & pharmaceutical bulletin 巻 30, 号 5, p. 1896-1899, 発行日 1982-05-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0009-2363 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00602100 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/cpb.30.1896 | |||||
出版者 | ||||||
出版者 | 日本薬学会 Pharmaceutical Society of Japan | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | An attempt was made to obtain more potent antitumor compounds by chemically modifying asterriquinones. Amino-and aziridinyl-asterriquinone were newly synthesized, but showed no activity. However, dimethylallylation of asterriquinone Cl, which had no effect in vivo, yielded an active compound, with a change in pKa value from 5.0 to 7.2. This suggests that other active compounds may be obtained by the chemical modification of asterriquinones with various other functional groups. | |||||
権利 | ||||||
権利情報 | Copyright © The Pharmaceutical Society of Japan | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://ci.nii.ac.jp/naid/110003634531/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | http://www.pharm.or.jp/ | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/article/cpb1958/30/5/30_5_1896/_article | |||||
関連URI | ||||||
識別子タイプ | URI | |||||
関連識別子 | https://japanlinkcenter.org/JST.Journalarchive/cpb1958/30.1896 |