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Hydrolysis of 5-Chloro-7-iodo-8-quinolinol Conjugates catalyzed by Metal Ions
http://hdl.handle.net/2297/44909
http://hdl.handle.net/2297/44909611de02a-69e7-4b44-b823-96573cb8b2f2
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PH-PR-HAYAKAWA-K-1411.pdf (374.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-04 | |||||
| タイトル | ||||||
| タイトル | Hydrolysis of 5-Chloro-7-iodo-8-quinolinol Conjugates catalyzed by Metal Ions | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Hayakawa, Kazuichi
× Hayakawa, Kazuichi× Chen, Chingtan× Imanari, Toshio× Tamura, Zenzo |
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| 書誌情報 |
Chemical and Pharmaceutical Bulletin 巻 24, 号 6, p. 1411-1413, 発行日 1976-01-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0009-2363 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00602100 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/cpb.24.1411 | |||||
| 出版者 | ||||||
| 出版者 | 日本薬学会 = The Pharmaceutical Society of Japan | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Glucuronide (CF-G) and sulfate (CF-S) of 5-chloro-7-iodo-8-quinolinol were hydrolyzed in water in the presence of metal ions at pH 7. In this condition, CF-G was hydrolyzed more easily than CF-S. The rate of the hydrolysis, pseudo-first order reaction, was in parallel with the stability constants of 8-quinolinol-metal complexes. The rate of hydrolysis increased with reduction of concentration of H+ and tris buffer suppressed the hydrolysis of CF-G. These results suggest that metal catalyzed hydrolysis of CF-G and CF-S was derived from the formation of complexes between the conjugates and metal ions. | |||||
| 権利 | ||||||
| 権利情報 | Copyright © The Pharmaceutical Society of Japan | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.pharm.or.jp/ | |||||
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| 識別子タイプ | URI | |||||
| 関連識別子 | https://www.jstage.jst.go.jp/browse/cpb/-char/ja/ | |||||
