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A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion
http://hdl.handle.net/2297/31375
http://hdl.handle.net/2297/3137528bcdb12-15a6-432c-a75e-2c36bb62c69f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HO-PR-WADA-T-376.pdf (166.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-10-05 | |||||
| タイトル | ||||||
| タイトル | A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Wada, Taizo
× Wada, Taizo× Nishimura, Kashiku× Kuroda, Mondo× Asai, Erika× Vu, Quang Van× Toma, Tomoko× Niida, Yo× Yachie, Akihiro |
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| 書誌情報 |
Brain and Development 巻 34, 号 5, p. 376-379, 発行日 2012-05-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0387-7604 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00111153 | |||||
| DOI | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.braindev.2011.07.005 | |||||
| 出版者 | ||||||
| 出版者 | Elsevier / 日本小児神経学会Japanese Society of Child Neurology | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We report on a 9-year-old boy who presented with acute encephalopathy and hemophagocytic lymphohistiocytosis (HLH). The patient was referred to our hospital because of fever, seizures, and decreased consciousness. He showed moderately elevated levels of proinflammatory cytokines in the cerebrospinal fluid and plasma, and clonal expansion of highly activated CD8 + T cells in the peripheral blood. These CD8 + T cells were found to be larger cells that stained positive for T-cell receptor Vβ13.6, and decreased shortly after steroid therapy. Our findings suggest that his acute encephalopathy was likely a clinical manifestation of HLH, and that immunophenotypic analysis may be helpful for early recognition of HLH in such rare encephalopathy. © 2011 The Japanese Society of Child Neurology. | |||||
| 権利 | ||||||
| 権利情報 | © 2011 The Japanese Society of Child Neurology | |||||
| 著者版フラグ | ||||||
| 出版タイプ | AM | |||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://child-neuro-jp.org/ | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.elsevier.com/locate/issn/03877604 | |||||
