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Contribution of sellar dura integrity to symptom manifestation in pituitary adenomas with intratumoral hemorrhage
https://doi.org/10.24517/00042063
https://doi.org/10.24517/00042063cecc50c1-976b-493f-9a88-cd47c984d815
| 名前 / ファイル | ライセンス | アクション |
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ME-PR-HAYASHI-Y-531.pdf (1.8 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||
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| 公開日 | 2017-11-17 | |||||||||||||||||
| タイトル | ||||||||||||||||||
| タイトル | Contribution of sellar dura integrity to symptom manifestation in pituitary adenomas with intratumoral hemorrhage | |||||||||||||||||
| 言語 | ||||||||||||||||||
| 言語 | eng | |||||||||||||||||
| 資源タイプ | ||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||
| ID登録 | ||||||||||||||||||
| ID登録 | 10.24517/00042063 | |||||||||||||||||
| ID登録タイプ | JaLC | |||||||||||||||||
| 著者 |
Hayashi, Yasuhiko
× Hayashi, Yasuhiko× Sasagawa, Yasuo× Kita, Daisuke× Fukui, Issei× Oishi, Masahiro× Tachibana, Osamu× Ueda, Fumiaki× Nakada, Mitsutoshi |
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| 著者別表示 |
林, 康彦
× 林, 康彦
× 笹川, 泰生
× 喜多, 大輔
× 立花, 修
× 植田, 文明
× 中田, 光俊
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| 書誌情報 |
Pituitary 巻 20, 号 5, p. 531-538, 発行日 2017-10-01 |
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| 収録物識別子タイプ | ISSN | |||||||||||||||||
| 収録物識別子 | 1386-341X | |||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||
| 収録物識別子 | AA11488255 | |||||||||||||||||
| DOI | ||||||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||
| 関連識別子 | 10.1007/s11102-017-0814-x | |||||||||||||||||
| 出版者 | ||||||||||||||||||
| 出版者 | Springer | |||||||||||||||||
| 抄録 | ||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||
| 内容記述 | Purpose: Although hemorrhage within pituitary adenomas frequently exacerbates the symptoms, there are many grades of severity. Moreover, the contributing factors for symptom severity are still controversial. Methods: This retrospective study included 82 patients who underwent transsphenoidal surgery for pituitary adenomas with intratumoral hemorrhage. The grades of preoperative symptoms were classified into group A, asymptomatic or minor symptoms; group B, moderate symptoms sufficient for complain; and group C, severe symptoms disturbing daily life. Results: The hemorrhage volume within an adenoma was significantly higher in group C (92.6%) than in groups A (48.6%) and B (58.7%). Both headache and diplopia were dominant in group C, occurring in 72.2% and 27.8% of the patients, respectively. In group C, there was no significant difference in frequency between adenoma extensions into the sphenoid sinus (0%) and involvement of the cavernous sinus of Knosp grade 4 (0%), and extensions into the suprasellar region were not common (38.9%). The most distinctive feature was that “no extrasellar extension” was found only in group C (41.2%), and “multidirectional extension” was not detected in this group (0%). Multiple regression analysis revealed that the most powerful determining factors were the high frequencies of intratumoral hemorrhage and lack of extrasellar and multidirectional extensions. Conclusion: Rapid volume expansion of a hematoma and lack of extension or unidirectional extension might lead to significant compression of the sellar and surrounding structures. Of note, the integrity of the sellar dura might contribute to the acute onset of symptom manifestations caused by hemorrhage in pituitary adenomas. © 2017 Springer Science+Business Media, LLC | |||||||||||||||||
| 内容記述 | ||||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||||
| 内容記述 | Embargo Period 12 months | |||||||||||||||||
| 権利 | ||||||||||||||||||
| 権利情報 | The final publication is available at www.springerlink.com/article/10.1007/s11102-017-0814-x | |||||||||||||||||
| 著者版フラグ | ||||||||||||||||||
| 出版タイプ | AM | |||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||
