| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-01-25 |
| タイトル |
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タイトル |
Multiple liver metastases of pancreatic solid pseudopapillary tumor treated with resection following chemotherapy and transcatheter arterial embolization: A case report |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| ID登録 |
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ID登録 |
10.24517/00049839 |
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ID登録タイプ |
JaLC |
| 著者 |
Tajima, Hidehiro
Takamura, Hiroyuki
Kitagawa, Hirohisa
Nakayama, Akira
Shoji, Masatoshi
Watanabe, Toshifumi
Tsukada, Tomoya
Nakanuma, Shinichi
Okamoto, Koichi
Sakai, Seisho
Kinoshita, Jun
Makino, Isamu
Nakamura, Keishi
Hayashi, Hironori
Oyama, Katsunobu
Inokuchi, Masafumi
Nakagawara, Hisatoshi
Miyashita, Tomoharu
Ninomiya, Itasu
Fushida, Sachio
Fujimura, Takashi
Wakayama, Tomohiko
Iseki, Shoichi
Ikeda, Hiroko
Ohta, Tetsuo
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| 著者別表示 |
田島, 秀浩
高村, 博之
北川, 裕久
中村, 信一
岡本, 浩一
木下, 淳
牧野, 勇
中村, 慶史
林, 泰寛
尾山, 勝信
井口, 雅史
中川原, 寿俊
宮下, 知治
二宮, 致
若山, 友彦
藤村, 隆
若山, 友彦
井関, 尚一
池田, 博子
太田, 哲生
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| 提供者所属 |
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内容記述タイプ |
Other |
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内容記述 |
金沢大学医薬保健研究域医学系 |
| 書誌情報 |
Oncology Letters
巻 9,
号 4,
p. 1733-1738,
発行日 2015-04
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1792-1074 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.3892/ol.2015.2967 |
| 出版者 |
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出版者 |
Spandidos Publications |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
A 33-year-old female was diagnosed with a solid pseudopapillary tumor (SPT) of the pancreas and multiple liver metastases at the Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital (Kanazawa, Japan). Distal pancreatectomy and postoperative systemic chemotherapy with gemcitabine (GEM) and S-1, an oral fluoropyrimidine derivative, was administered, however, liver metastases became enlarged and local recurrence occurred. Therefore, the patient was referred to the Department of Gastroenterologic Surgery at the Graduate School of Medicine (Kanazawa, Japan) for hepatic arterial infusion (HAI) chemotherapy. Oral S-1 (80 mg/m2) was administered as well as HAI chemotherapy with GEM (1,000 mg/standard liver volume). Following 18 cycles, tumor sizes were reduced and 18-fluorodeoxyglucose positron emission tomography (18FDG-PET) examination revealed obvious reduction of tumor FDG uptake. Transarterial tumor embolization (TAE) was performed for the previously unresectable right subphrenic liver tumor, and the other tumors were surgically resected. The resected tumors were diagnosed as liver metastases and a local recurrence of SPT in the postoperative pathological examination, which revealed that the resected tumors were composed of sheets of bland cells, which were positive for CD10, CD56, vimentin, neuron-specific enolase and α-antitrypsin. The postoperative course was uneventful, and the patient is currently under observation at an outpatient clinic; postoperative adjuvant chemotherapy with oral S-1 has continued, and additional TAE is planned. In the future, if the middle segment of the liver becomes enlarged, surgery for the residual right lobe tumor may be possible. This case demonstrates one method of SPT treatment: Preoperative HAI chemotherapy with GEM, plus oral S-1 and TAE. If complete resection can be achieved, the majority of patients with SPT have a favorable prognosis. In patients with unresectable metastases from SPT, it is crucial to conduct systematic multimodal treatment to maximize treatment success. © 2015, Spandidos Publications. All Rights Reserved. |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Embargo Period 6 months |
| 権利 |
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|
権利情報 |
Copyright © Spandidos Publications |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
ME-PR-ISEKI-S-1733.pdf (1.2 MB)
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