| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2018-04-13 |
| タイトル |
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タイトル |
Objective evaluation of cerebrovascular reactivity for acetazolamide predicts cerebral hyperperfusion after carotid artery stenting: Comparison with region of interest methods |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| ID登録 |
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ID登録 |
10.24517/00050486 |
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ID登録タイプ |
JaLC |
| 著者 |
Misaki, Koichi
Uchiyama, Naoyuki
Inaki, Anri
Kinuya, Seigo
Nambu, Iku
Kamide, Tomoya
Mohri, Masanao
Hayashi, Yasuhiko
Nakada, Mitsutoshi
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| 著者別表示 |
見崎, 孝一
内山, 尚之
稲木, 杏吏
絹谷, 清剛
林, 康彦
中田, 光俊
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| 提供者所属 |
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内容記述タイプ |
Other |
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内容記述 |
金沢大学附属病院脳神経外科 |
| 書誌情報 |
Journal of Neuroradiology
巻 45,
号 6,
p. 362-367,
発行日 2018-10
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0150-9861 |
| NCID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA0025864X |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
10.1016/j.neurad.2018.02.008 |
| 出版者 |
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出版者 |
Elsevier Masson SAS |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background and purpose: Hemodynamic impairments are considered risk factors of cerebral hyperperfusion after carotid artery stenting (CAS); measurement by Single-photon emission computed tomography (SPECT) using a subjective region of interest (ROI) method lacks consistency and reproducibility. Materials and methods: The present study compared objective perfusion analysis (stereotactic extraction estimation [SEE] method) with the ROI method for preoperative SPECT to predict the hyperperfusion phenomenon (HPP) after CAS. Preoperative resting asymmetry index (cerebral blood flow [CBF] ratio from the affected to unaffected hemisphere) and cerebrovascular reactivity (CVR) to acetazolamide were measured by N-isopropyl-p-[123I]-iodoamphetamine SPECT using the SEE and ROI method in 84 patients. CBF was also measured the day after CAS. Perfusion data with the highest area under the curve (AUC) by receiver-operating characteristic (ROC) analysis was considered a perfusion risk factor of HPP. Multivariate analyses for clinical characteristics and perfusion risk factors were performed to determine predictors of HPP. Results: The HPP was observed in 10 patients (11.9%). Female sex, contralateral stenosis, and degree of stenosis were significantly associated with HPP development on univariate analysis, and symptomatic stenosis was not found to be a significant factor. On SPECT analysis, CVR in the MCA area by SEE method had the highest AUC (0.981). Multivariate analysis showed that CVR in the MCA area was a significant predictor of HPP (P = 0.041). To predict hyperperfusion, the ROC curve of the CVR showed a cutoff value of –0.60%, sensitivity of 94.6%, and specificity of 100% (P < 0.001). Conclusions: Objective SEE method had better a predictive capability than ROI method to identify risk of hyperperfusion after CAS. © 2018 Elsevier Masson SAS |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Embargo Period 12 months |
| 権利 |
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権利情報 |
Copyright © 2018 Elsevier Masson SAS |
| 著者版フラグ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
http://www.elsevier.com/locate/issn/00142980 |
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関連名称 |
http://www.elsevier.com/locate/issn/00142980 |
| 関連URI |
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識別子タイプ |
URI |
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関連識別子 |
https://seikagaku.jbsoc.or.jp/ |
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関連名称 |
https://seikagaku.jbsoc.or.jp/ |
ME-PR-MISAKI-K-362.pdf (723.3 kB)
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