{"_buckets": {"deposit": "e76cad25-cacd-4503-b9a1-0df6e13332df"}, "_deposit": {"created_by": 18, "id": "52775", "owners": [18], "pid": {"revision_id": 0, "type": "depid", "value": "52775"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00052775", "sets": ["4014"]}, "author_link": ["61534", "75167"], "item_9_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2021-05-05", "bibliographicIssueDateType": "Issued"}, "bibliographicPageStart": "4p.", "bibliographicVolumeNumber": "2019-04-01 – 2021-03-31", "bibliographic_titles": [{"bibliographic_title": "令和2(2020)年度 科学研究費補助金 若手研究 研究成果報告書"}, {"bibliographic_title": "2020 Fiscal Year Final Research Report", "bibliographic_titleLang": "en"}]}]}, "item_9_creator_33": {"attribute_name": "著者別表示", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Oishi, Kyosuke"}], "nameIdentifiers": [{"nameIdentifier": "75167", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60735398", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60735398"}]}]}, "item_9_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "我々の以前の研究で多発性筋炎の重症化に接着分子の一つであるL-selectinが関与する可能性が示唆された。本研究は、多発性筋炎のモデルマウスであるCIMに対し、selectinの阻害剤であるBimosiamoseを投与することにより、同分子が多発性筋炎の治療の標的となり得るかどうか検討するものである。現在、Bimosiamoseの投与量、投与スケジュールなどを検討している段階である。投与量、スケジュール等が決定すればCIMに投与を行い、筋炎の重症度を比較する予定である。", "subitem_description_type": "Abstract"}, {"subitem_description": "Our previous study revealed the possibility that L-selectin, one of the adhesion molecule, involve in severity of polymyositis. This study can reveal whether the L-selectin could be the therapeutic target for polymyositis by administration of bimosiamose, a one of the selectin inhibitor, to mouse model of polymyositis. We are considering about dosage, duration, and frequency of bimosiamose. When we make a decision about these points, we administrate bimosiamose to mouse model of polymyositis, and make a comparison of severity of myositis.", "subitem_description_type": "Abstract"}]}, "item_9_description_22": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "研究課題/領域番号:19K17765, 研究期間(年度):2019-04-01 – 2021-03-31", "subitem_description_type": "Other"}, {"subitem_description": "出典：「多発性筋炎モデルマウスに対するSelectin阻害剤の治療効果の検討」研究成果報告書　課題番号19K17765\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K17765/19K17765seika/）を加工して作成", "subitem_description_type": "Other"}]}, "item_9_description_5": {"attribute_name": "提供者所属", "attribute_value_mlt": [{"subitem_description": "金沢大学医薬保健研究域医学系", "subitem_description_type": "Other"}]}, "item_9_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.24517/00059068", "subitem_identifier_reg_type": "JaLC"}]}, "item_9_relation_28": {"attribute_name": "関連URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "https://kaken.nii.ac.jp/ja/search/?kw=60735398"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://kaken.nii.ac.jp/ja/search/?kw=60735398", "subitem_relation_type_select": "URI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19K17765/"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19K17765/", "subitem_relation_type_select": "URI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K17765/19K17765seika/"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://kaken.nii.ac.jp/ja/report/KAKENHI-PROJECT-19K17765/19K17765seika/", "subitem_relation_type_select": "URI"}}]}, "item_9_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "大石, 京介"}], "nameIdentifiers": [{"nameIdentifier": "61534", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60735398", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60735398"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-02-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-OISHI-K-kaken 2021-4p.pdf", "filesize": [{"value": "68.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 68500.0, "url": {"label": "ME-PR-OISHI-K-kaken 2021-4p.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/52775/files/ME-PR-OISHI-K-kaken 2021-4p.pdf"}, "version_id": "532ace7b-d99c-44c6-b717-84a18727a834"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "多発性筋炎", "subitem_subject_scheme": "Other"}, {"subitem_subject": "L-selectin", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "research report", "resourceuri": "http://purl.org/coar/resource_type/c_18ws"}]}, "item_title": "多発性筋炎モデルマウスに対するSelectin阻害剤の治療効果の検討", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "多発性筋炎モデルマウスに対するSelectin阻害剤の治療効果の検討"}, {"subitem_title": "Consideration of the therapoitic effect of selectin inhibitor in a mouse model of polymyositis.", "subitem_title_language": "en"}]}, "item_type_id": "9", "owner": "18", "path": ["4014"], "permalink_uri": "https://doi.org/10.24517/00059068", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-02-25"}, "publish_date": "2022-02-25", "publish_status": "0", "recid": "52775", "relation": {}, "relation_version_is_last": true, "title": ["多発性筋炎モデルマウスに対するSelectin阻害剤の治療効果の検討"], "weko_shared_id": -1}