| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2017-10-03 |
| タイトル |
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|
タイトル |
One-pot stereoselective synthesis of 2-acylaziridines and 2-acylpyrrolidines from N-(propargylic)hydroxylamines |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.24517/00010573 |
|
ID登録タイプ |
JaLC |
| 著者 |
Miyamoto, Yoshiaki
Wada, Norihiro
Soeta, Takahiro
Fujinami, Shuhei
Inomata, Katsuhiko
Ukaji, Yutaka
|
| 著者別表示 |
添田, 貴宏
藤波, 修平
猪股, 勝彦
宇梶, 裕
|
| 書誌情報 |
Chemistry - An Asian Journal
巻 8,
号 4,
p. 824-831,
発行日 2013-04-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1861-4728 |
| NCID |
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収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA12151701 |
| DOI |
|
|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
10.1002/asia.201201180 |
| 出版者 |
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|
出版者 |
Wiley-VCH Verlag Berlin |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
The stereoselective direct transformation of N-(propargylic)hydroxylamines into cis-2-acylaziridines was achieved by the combined use of AgBF4 and CuCl. Copper salts were found to promote the transformation of the intermediary 4-isoxazolines into 2-acylaziridines and both 3-aryl- and 3-alkyl-substituted 2-acylaziridines could be prepared by using this method. Furthermore, subsequent 1,3-dipolar cycloaddition of azomethine ylides that were generated in situ from the intermediary 2-acylaziridines with maleimides was achieved in a stereoselective one-pot procedure to afford the corresponding 2-acylpyrrolidines, which consisted of an octahydropyrrolo[3,4-c]pyrrole skeleton. Love the way ylide: The transformation of N-(propargylic) hydroxylamines into cis-2-acylaziridines and subsequent 1,3-dipolar cycloaddition of the in situ generated azomethine ylides with maleimides stereoselectively afforded 2-acylpyrrolidines. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| 著者版フラグ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
SC-PR-UKAJI-Y-824.pdf (643.9 kB)
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