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Prolactin inhibits osteoclastic activity in the goldfish scale: A novel direct action of prolactin in teleosts
http://hdl.handle.net/2297/14428
http://hdl.handle.net/2297/1442828f09807-8987-4379-add9-e4caf226fbb0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
INE-PR-SUZUKI-N-739.pdf (544.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2017-10-05 | |||||
| タイトル | ||||||
| タイトル | Prolactin inhibits osteoclastic activity in the goldfish scale: A novel direct action of prolactin in teleosts | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Takahashi, Hideya
× Takahashi, Hideya× Suzuki, Nobuo× Takagi, Chiyo× Ikegame, Mika× Yamamoto, Toshio× Takahashi, Akiyoshi× Moriyama, Shunsuke× Hattori, Atsuhiko× Sakamoto, Tatsuya |
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| 書誌情報 |
Zoological Science 巻 25, 号 7, p. 739-745, 発行日 2008-07-01 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0289-0003 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA10545874 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.2108/zsj.25.739 | |||||
| 出版者 | ||||||
| 出版者 | the Zoological Society of Japan = 日本動物学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In teleosts, prolactin is involved in calcium regulation, but its role in scale/bone metabolism Is unclear. Using the in-vitro system with goldfish scales developed recently, we explored the effects of teleost prolactin, growth hormone, and somatolactin on osteoclasts and osteoblasts. Addition of prolactin at concentrations of 0.01-100 ng/ml reduced osteoclastic activity, partly via osteoclast apoptosis, after 6-18 h incubation. Conversely, growth hormone and somatolactin at a concentration of 100 ng/ml increased osteoclastic activity after 18 h incubation, indicating the specificity of the inhibitory effect of prolactin on osteoclastic activity. On the other hand, these three hormones promoted osteoblastic activity at concentrations of 10-100 ng/ml. The results from this study are the first demonstration of direct effects of prolactin on scale/bone metabolism and osteoclastic activity in a teleost. © 2008 Zoological Society of Japan. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 関連URI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | http://dx.doi.org/10.2108/zsj.25.739 | |||||
| 関連URI | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.bioone.org/doi/abs/10.2108/zsj.25.739 | |||||
