WEKO3
インデックスリンク
アイテム
{"_buckets": {"deposit": "b584f637-55fe-4ec7-8573-aac038f2729c"}, "_deposit": {"created_by": 3, "id": "14275", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "14275"}, "status": "published"}, "_oai": {"id": "oai:kanazawa-u.repo.nii.ac.jp:00014275", "sets": ["4312"]}, "author_link": ["24590", "72", "371", "2865", "332", "23291"], "item_4_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-10-01", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "692", "bibliographicPageStart": "685", "bibliographicVolumeNumber": "854", "bibliographic_titles": [{"bibliographic_title": "Advances in Experimental Medicine and Biology"}]}]}, "item_4_creator_33": {"attribute_name": "著者別表示", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "大貝, 和裕"}], "nameIdentifiers": [{"nameIdentifier": "2865", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40706983", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40706983"}]}, {"creatorNames": [{"creatorName": "杉谷, 加代"}], "nameIdentifiers": [{"nameIdentifier": "371", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "20162258", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20162258"}, {"nameIdentifier": "20162258", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000020162258"}]}, {"creatorNames": [{"creatorName": "郡山, 恵樹"}], "nameIdentifiers": [{"nameIdentifier": "332", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70397199", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70397199"}, {"nameIdentifier": "70397199", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070397199"}]}, {"creatorNames": [{"creatorName": "加藤, 聖"}], "nameIdentifiers": [{"nameIdentifier": "72", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10019614", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10019614"}, {"nameIdentifier": "10019614", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010019614"}]}]}, "item_4_description_21": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Zebrafish can regenerate several organs such as the tail fin, heart, central nervous system, and photoreceptors. Very recently, a study has demonstrated the photoreceptor regeneration in the alkylating agent N-methyl-N-nitrosourea (MNU)- induced retinal degeneration (RD) zebrafish model, in which whole photoreceptors are lost within a week after MNU treatment and then regenerated within a month. The research has also shown massive proliferation of Müller cells within a week. To address the question of whether proliferating Müller cells are the source of regenerating photoreceptors, which remains unknown in the MNU-induced zebrafish RD model, we employed a BrdU pulse-chase technique to label the proliferating cells within a week after MNU treatment. As a result of the BrdU pulse-chase technique, a number of BrdU+ cells were observed in the outer nuclear layer as well as the inner nuclear layer. This implies that regenerating photoreceptors are derived from proliferating Müller cells in the zebrafish MNU-induced RD model. © Springer International Publishing Switzerland 2016.", "subitem_description_type": "Abstract"}]}, "item_4_description_22": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "[Book Chapter]", "subitem_description_type": "Other"}]}, "item_4_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.24517/00014262", "subitem_identifier_reg_type": "JaLC"}]}, "item_4_publisher_17": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Springer"}]}, "item_4_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1007/978-3-319-17121-0_91", "subitem_relation_type_select": "DOI"}}]}, "item_4_rights_23": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "The final publication is available at www.springerlink.com/article/chapter/10.1007%2F978-3-319-17121-0_91"}]}, "item_4_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00512642", "subitem_source_identifier_type": "NCID"}]}, "item_4_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0065-2598", "subitem_source_identifier_type": "ISSN"}]}, "item_4_version_type_25": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ogai, Kazuhiro"}], "nameIdentifiers": [{"nameIdentifier": "23291", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "40706983", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40706983"}]}, {"creatorNames": [{"creatorName": "Hisano, Suguru"}], "nameIdentifiers": [{"nameIdentifier": "24590", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sugitani, Kayo"}], "nameIdentifiers": [{"nameIdentifier": "371", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "20162258", "nameIdentifierScheme": "金沢大学研究者情報", "nameIdentifierURI": "http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20162258"}, {"nameIdentifier": "20162258", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000020162258"}]}, {"creatorNames": [{"creatorName": "Koriyama, Yoshiki"}], "nameIdentifiers": [{"nameIdentifier": "332", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "70397199", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=70397199"}, {"nameIdentifier": "70397199", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000070397199"}]}, {"creatorNames": [{"creatorName": "Kato, Satoru"}], "nameIdentifiers": [{"nameIdentifier": "72", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "10019614", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10019614"}, {"nameIdentifier": "10019614", "nameIdentifierScheme": "研究者番号", "nameIdentifierURI": "https://nrid.nii.ac.jp/nrid/1000010019614"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-10-03"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ME-PR-OOGAI-K-685.pdf", "filesize": [{"value": "363.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 363500.0, "url": {"label": "ME-PR-OOGAI-K-685.pdf", "url": "https://kanazawa-u.repo.nii.ac.jp/record/14275/files/ME-PR-OOGAI-K-685.pdf"}, "version_id": "6714e96a-ee32-4d78-b756-bb69e04916f7"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Cell proliferation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Müller cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "N-methyl-Nnitrosourea (MNU)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Photoreceptor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Regeneration", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Zebrafish", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Cell fate of müller cells during photoreceptor regeneration in an N-methyl-N-nitrosourea- induced retinal degeneration model of zebrafish", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Cell fate of müller cells during photoreceptor regeneration in an N-methyl-N-nitrosourea- induced retinal degeneration model of zebrafish"}]}, "item_type_id": "4", "owner": "3", "path": ["4312"], "permalink_uri": "https://doi.org/10.24517/00014262", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-10-03"}, "publish_date": "2017-10-03", "publish_status": "0", "recid": "14275", "relation": {}, "relation_version_is_last": true, "title": ["Cell fate of müller cells during photoreceptor regeneration in an N-methyl-N-nitrosourea- induced retinal degeneration model of zebrafish"], "weko_shared_id": 3}
Cell fate of müller cells during photoreceptor regeneration in an N-methyl-N-nitrosourea- induced retinal degeneration model of zebrafish
https://doi.org/10.24517/00014262
https://doi.org/10.24517/00014262e78c7c65-d38d-49a8-83db-5aba0ddabd66
名前 / ファイル | ライセンス | アクション |
---|---|---|
ME-PR-OOGAI-K-685.pdf (363.5 kB)
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-10-03 | |||||
タイトル | ||||||
タイトル | Cell fate of müller cells during photoreceptor regeneration in an N-methyl-N-nitrosourea- induced retinal degeneration model of zebrafish | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.24517/00014262 | |||||
ID登録タイプ | JaLC | |||||
著者 |
Ogai, Kazuhiro
× Ogai, Kazuhiro× Hisano, Suguru× Sugitani, Kayo× Koriyama, Yoshiki× Kato, Satoru |
|||||
著者別表示 |
大貝, 和裕
× 大貝, 和裕× 杉谷, 加代× 郡山, 恵樹× 加藤, 聖 |
|||||
書誌情報 |
Advances in Experimental Medicine and Biology 巻 854, p. 685-692, 発行日 2016-10-01 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0065-2598 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00512642 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/978-3-319-17121-0_91 | |||||
出版者 | ||||||
出版者 | Springer | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Zebrafish can regenerate several organs such as the tail fin, heart, central nervous system, and photoreceptors. Very recently, a study has demonstrated the photoreceptor regeneration in the alkylating agent N-methyl-N-nitrosourea (MNU)- induced retinal degeneration (RD) zebrafish model, in which whole photoreceptors are lost within a week after MNU treatment and then regenerated within a month. The research has also shown massive proliferation of Müller cells within a week. To address the question of whether proliferating Müller cells are the source of regenerating photoreceptors, which remains unknown in the MNU-induced zebrafish RD model, we employed a BrdU pulse-chase technique to label the proliferating cells within a week after MNU treatment. As a result of the BrdU pulse-chase technique, a number of BrdU+ cells were observed in the outer nuclear layer as well as the inner nuclear layer. This implies that regenerating photoreceptors are derived from proliferating Müller cells in the zebrafish MNU-induced RD model. © Springer International Publishing Switzerland 2016. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | [Book Chapter] | |||||
権利 | ||||||
権利情報 | The final publication is available at www.springerlink.com/article/chapter/10.1007%2F978-3-319-17121-0_91 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |